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Animal Testing Alternatives and Invitro Efficacy Test

  • Invirto Efficacy Testing

    Whitening Test

       ? Tyrosinase Inhibition Test
       ? Melanocyte Inhibition Test

    Anti-aging Test

       ? Human Fibroblast Safe Concentration Screening
       ? β-galactosidase assay
       ? Determination of collagen content
       ? Determination of MMP-1 content


  • Invirto Efficacy Testing

    Anti-oxidant Test

       ? HaCat Safe Concentration Screening
       ? HaCat Anti-oxidant Test (ROS)
       ? HaCat Anti-oxidant Test (SOD)
       ? HaCat Anti-oxidant Test (MDA)

    Anti-acne Test

       ? Inhibition test of Propionibacterium acne
       ? Anti-inflammatory test

    Anti-allergic Test

       ? β－β-aminohexosidase assay
       ? Determination of histam


  • Animal Testing Alternatives

    Cytotoxicity：

        Keratinocytes Cytotoxicity Test

    Eye Irritation Test：

        Short-term exposure test of rabbit corneal epithelial cells in vitro

    Skin Sensitization Test：

        h-CLAT Skin Sensitization Test：
        Local lymph node cell Test：DA
        Local lymph node cell Test：BrdU


    • Human Safety and Efficacy Test

  • 1Human Efficacy Test on Face

    Moisturizing Test (Short- & Long-term)
    Skin Barrier Function Test
    Skin Whitening Test
    Skin Depigment Test

    Skin Anti-wrinkle & Anti-aging Test (Facial 

    wrinkle and Nasolabial folds)

    Skin Oil-control Test
    Skin Pore Test
    Skin Exfoliating Test
    Skin Soothing Test

  • 2Human Efficacy Test on Eye and lip

    Moisturizing Test（Short- & Long-term）

    Skin Anti-wrinkle & Anti-aging Test （

    Crow's feet & Wrinkle under eyes）

    Dark circles Improvement Test
    Pouch Improvement Test

  • 3Human Safety Test

    Human Skin Patch Test
    Repeat Open Application Test
    Lactic Acid Irritation Test

  • 4Sensory Evaluation

    Objective Evaluation
    Subjective Evaluation
    Consumer Research

    • Fundamental parameters of Human Efficacy Test

    ? VISIA （Facial skin imaging test）
    ? PRIMOS CR （Wrinkle test）
    ? Coneometer（Skin moisture test）
    ? Tewameter（TEWL test）
    ? Chromameter/CM2600D（Skin color test）
    ? Cutometer（Skin elasticity test）
    ? Mexameter（Skin melanin and red pigment test）
    ? Sebumeter（Skin and scalp oil test）
    ? PH meter（Skin PH test）

    Procedure

    • Design

      Project evaluation, design of the test scheme and implementation plan

    • Preparation

      Formulation of test implementation documents and Signing of test agreement

    • Implementation

      Volunteer recruitment, implementation, monitoring and feedback of the process

    • Statistical analysis

      Data processing and analysis, data storage, editing and submission of report

    • Ending

      Comprehensive review of documents, archiving of project data

    Contact

    TYRAN Enterprise Management (Guangzhou) Co., Ltd.

    Add：Heyu Industrial Park, No. 64, Songshan Road, Shilou Town, Panyu District, Guangzhou City, Guangdong Province

    Tel：020-84868986

    Fax：020-39139611

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